Thursday, August 11, 2011

Biochemistry Question?

An antibiotic named fixmycin, which was isolated from a fungus on ripe pion fruit, is effective in curing many types of venereal disease. In characterizing fixmycin’s mode of action, you have found that it is a bacterial translational inhibitor that binds exclusively to the large subunit of E. coli ribosomes. The initiation of protein synthesis in the presence of fixmycin always results in the generation of dipeptides that remain ociated with the ribosome. Suggest a mode of action for fixmycin.

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